منابع مشابه
Herpesviruses and human cancer.
Although it has been established that some viruses can cause cancer in animals, the evidence for a viral etiology of at least some human cancers has been slow to accumulate. At present, viruses acting alone or in association with such factors as hormones, chemicals, genetic determinants, or other unknown cofactors have been linked to five human cancers (see Table 1). Three of these malignancies...
متن کاملFrequency and stability of chromosomal integration of adenovirus vectors.
One of the limitations of adenovirus vectors is the lack of machinery necessary for their integration into host chromosomes, resulting in short-term gene expression in dividing cells. We analyzed frequencies of integration and persistence of gene expression from integrated adenovirus vectors. Both E1-substituted and helper-dependent adenovirus vectors achieved similar integration efficiencies o...
متن کاملHuman Herpesviruses 6 and 7
The identification of human herpesvirus (HHV) 6 (HHV-6) and 7 (HHV-7) was first reported in 1986 and 1990, respectively. HHV-6 was isolated initially from the blood of several immunodeficient adults, including some with acquired immunodeficiency syndrome (AIDS) (1). The existence of HHV-7 was first revealed in the blood of a healthy, human immunodeficiency virus (HIV)-negative adult (2). Extens...
متن کاملHerpesviruses that Infect Fish
Herpesviruses are host specific pathogens that are widespread among vertebrates. Genome sequence data demonstrate that most herpesviruses of fish and amphibians are grouped together (family Alloherpesviridae) and are distantly related to herpesviruses of reptiles, birds and mammals (family Herpesviridae). Yet, many of the biological processes of members of the order Herpesvirales are similar. A...
متن کاملUnderstanding Primate Herpesviruses
Viruses related to the herpes simplex viruses of humans are present in all nonhuman primate (NHP) species tested and cross species transmission has been documented. The herpesvirus present in macaques, Herpes B virus (BV) rarely causes disease in its natural macaque host. However, when transmitted to a nonnative host, BV has occasionally caused severe and even fatal disease if not treated immed...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2010
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.01169-10